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Chemotherapy Induced Peripheral Neuropathy, Sleep and Quality of Life among Patients with Gastric Cancer Receiving Chemotherapy

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KMID : 0388320180250030176
±èÇý¹Ì ( Kim Hye-Mi ) - ÀÌÈ­¿©ÀÚ´ëÇб³ Àӻ󺸰ÇÀ¶ÇÕ´ëÇпø

¹ÚÈ¿Á¤ ( Park Hyo-Jung ) - ÀÌÈ­¿©ÀÚ´ëÇб³ °£È£´ëÇÐ

Abstract

Purpose: Purpose of this study was to investigate relationships and influence of peripheral neuropathy, sleep, and quality of life in patients with gastric cancer who are receiving chemotherapy.

Methods: Participants were 131 patients with gastric cancer being treated at a chemotherapy outpatient clinic and receiving chemotherapy. Data were analyzed using descriptive statistics, t-test, ANOVA, and multiple regression analysis with the SPSS program.

Results: Mean score for peripheral neuropathy was 24.66, for sleep, 6.71 and for quality of life, 67.69. Peripheral neuropathy had a significant positive correlation with sleep (r=.26, p=.003) and sleep had a significant negative correlation with quality of life (r=-.50, p<.001). The regression model explaining quality of patients¡¯lives was significant (F=11.91, p<.001), peripheral neuropathy, sleep, and pain due to anticancer drugs and number ofneurotoxic anticancer drugs explained 25.1% of the variance in quality of life and sleep was the most important factor.

Conclusion: To improve the quality of life for these patients, individualized nursing interventions for pain should be provided according to number of anticancer drugs in the chemotherapy. Also there is a need to identify ways to assess peripheral neuropathy and sleep disorders that are appropriate in the treatment and reduce side effects during treatment.
KeyWords
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Chemotherapy adjuvant, Stomach neoplasms, Peripheral neuropathy, Sleep, Quality of life
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ÇмúÁøÈïÀç´Ü(KCI) KoreaMed